speak to your medical professional with regard to the hazards and benefits of getting promethazine if you are 65 years of age or more mature. More mature Older people should not generally take promethazine since it just isn't as Harmless as other remedies that may be applied to deal with a similar situations.

Carcinogenicity, mutagenicity, and fertility reports haven't been carried out with Promethazine with Codeine Oral Alternative; even so, posted info is readily available for the person Energetic elements.

Promethazine hydrochloride was not mutagenic in the in vitro bacterial reverse mutation assay or clastogenic during the in vitro Chinese hamster ovary (CHO) mobile chromosomal aberration assay.

The dose of the medicine will be unique for different individuals. Stick to your medical professional's orders or the directions to the label. The next facts consists of only the typical doses of this drugs. Should your dose is different, never alter it Unless of course your doctor tells you to do so.

If a affected person requires a refill, reevaluate the reason for the cough and evaluate the need for continued cure with Promethazine with Codeine Oral Solution, the relative incidence of adverse reactions, and the development of habit, abuse, or misuse.

This medication can dry up and thicken mucus with your lungs, making it more difficult to breathe and clear your lungs. To assist prevent this outcome, drink loads of fluids unless in any other case directed by your medical doctor.

Get health care assistance instantly when you notice any of the subsequent: slow/shallow breathing, severe drowsiness/issues waking up, confusion.

The exact mechanism of motion of codeine and various opiates is not really recognised; nevertheless, codeine is believed to act centrally about the cough Middle. In abnormal doses, codeine will depress respiration.

In case you Promethazine codeine syrup are offering promethazine to a kid, observe the kid to be sure she or he doesn't get damage though Using a bike or participating in other things to do that could be dangerous.

In the event the affected person is physically dependent on opioids, the administration of opioid antagonists may well precipitate acute withdrawal syndrome. For that reason, clinicians really should prescribe opioid antagonists cautiously in individuals with physical opioid dependence, and decreased dosages of antagonists ought to be regarded for identified dependent people.

Promethazine with Codeine Oral Alternative is made up of codeine, a Timetable V controlled compound. As an opioid, Promethazine with Codeine Oral Resolution exposes consumers towards the dangers of dependancy, abuse, and misuse [see Drug Abuse and Dependence (9)], which can result in overdose and Loss of life [see Overdosage (ten)]. Reserve Promethazine with Codeine Oral Solution to be used in adult clients for whom some great benefits of cough suppression are predicted to outweigh the hazards, As well as in whom an satisfactory assessment on the etiology on the cough has actually been made. Assess Just about every affected person's hazard ahead of prescribing Promethazine with Codeine Oral Remedy, prescribe Promethazine with Codeine Oral Resolution for that shortest length that is certainly consistent with individual affected individual remedy ambitions, monitor all sufferers consistently for the event of dependancy or abuse, and refill only just after reevaluation of the necessity for ongoing treatment.

Promethazine with Codeine Oral Remedy could trigger severe hypotension which include orthostatic hypotension and syncope in ambulatory individuals. There is elevated possibility in clients whose capability to keep up hypertension has now been compromised by a lowered blood volume or concurrent administration of particular CNS depressant medications (e.

A doctor can make the clinical decision as to whether an opioid medication is well suited for an individual and which opioid to prescribe.

Making use of Liquor or tobacco with specific medicines may also trigger interactions to arise. The subsequent interactions have already been selected on the basis of their prospective significance and therefore are not automatically all-inclusive.